Dr. Margolis received his Bachelor of Science degree in biology from The University of Illinois, Urbana-Champaign. He attended the Chicago College of Osteopathic Medicine, where he attained the degree of Doctor of Osteopathic Medicine. He moved to Florida to intern at the Community Hospital of South Broward and began private practice in Family Medicine. He is board certified by The American Osteopathic Board of Family Practice, is a clinical assistant professor for Nova Southeastern University, and is an active member of the Broward County Osteopathic Association, Florida Osteopathic Association, and American Osteopathic Association.

Dr. Margolis is an avid tennis player, who enjoys a good movie or play with his wife, but is most proud of his title of Zaide (grandfather) to his seven grandchildren.